Raw Ganirelix powder is an injectable competitive gonadotropin-releasing hormone antagonist (a decapeptide GnRH antagonist). It is primarily used in assisted reproduction to control ovulation. The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH. Raw Ganirelix powder is used in fertility treatment to prevent premature ovulation that could result in the harvesting of eggs that are too immature to be used in procedures such as in vitro fertilisation. Raw Ganirelix powder is marketed by Merck & Co., Inc. as Orgalutran.
Raw Ganirelix powder is rapidly absorbed following subcutaneous injection with maximum serum concentrations reached approximately one hour after dosing. Product Name Raw Ganirelix powder Chemical Name Ac-DNal-DCpa-DPal-Ser-Tyr-DHar(Et2)-Leu-Har(Et2)-Pro-DAla -NH2;Raw Ganirelix powderum Brand Name Orgalutran, Antagon Drug Class Peptide CAS Number 124904-93-4 (123246-29-7) InChIKey GJNXBNATEDXMAK-PFLSVRRQSA-N Molecular Formula C80H113ClN18O13 Molecular Weight 1570.347 g/mol Monoisotopic Mass 1568.842 g/mol Melting Point N/A Biological Half-Life 16.2 hours Color White Solubility 0.25mg/ml~30mg/ml in DMSO and DMF Storage Temperature −20°C Application a Gonadotropin Releasing Hormone Antagonist, used in assisted reproduction to control ovulation.
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